A conserved mRNA expression profile of SREB2 (GPR85) in adult human, monkey, and rat forebrain
M Matsumoto, S Beltaifa, CS Weickert… - Molecular brain …, 2005 - Elsevier
SREB is a subfamily of G-protein-coupled receptors, which consists of SREB1 (GPR27),
SREB2 (GPR85), and SREB3 (GPR173). Its high evolutionary conservation and
predominant expression in the CNS suggest that SREB family members and their
undiscovered ligand (s) may have significant functions in the nervous system. SREB2 is the
most conserved receptor throughout vertebrate evolution. As a first step in understanding the
function of the SREB family, we have determined the anatomical gene expression profile of …
SREB2 (GPR85), and SREB3 (GPR173). Its high evolutionary conservation and
predominant expression in the CNS suggest that SREB family members and their
undiscovered ligand (s) may have significant functions in the nervous system. SREB2 is the
most conserved receptor throughout vertebrate evolution. As a first step in understanding the
function of the SREB family, we have determined the anatomical gene expression profile of …