Molecular and biochemical aspects of the PD-1 checkpoint pathway

VA Boussiotis - New England Journal of Medicine, 2016 - Mass Medical Soc
New England Journal of Medicine, 2016Mass Medical Soc
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The PD-1 pathway plays an essential role in maintaining immunologic self-tolerance. However, cancers can subvert the role of this pathway and blind the immune system to their presence. The molecular details of the pathway are discussed.
The New England Journal Of Medicine