[HTML][HTML] Copy number analysis of the murine platelet proteome spanning the complete abundance range
M Zeiler, M Moser, M Mann - Molecular & Cellular Proteomics, 2014 - ASBMB
Knowledge of the identity and quantity of expressed proteins of a cell type is a prerequisite
for a complete understanding of its molecular functions. Mass-spectrometry-based
proteomics has allowed the identification of the entire protein complement of yeast and the
close-to-complete set of proteins expressed in mammalian cell lines. Using recent
technological advances, we here characterized the proteome of murine platelets, key actors
in mediating hemostasis and thrombosis. We accurately measured the absolute protein …
for a complete understanding of its molecular functions. Mass-spectrometry-based
proteomics has allowed the identification of the entire protein complement of yeast and the
close-to-complete set of proteins expressed in mammalian cell lines. Using recent
technological advances, we here characterized the proteome of murine platelets, key actors
in mediating hemostasis and thrombosis. We accurately measured the absolute protein …