[HTML][HTML] Contemporary use of β-blockers: clinical relevance of subclassification

L Poirier, SW Tobe - Canadian Journal of Cardiology, 2014 - Elsevier
Abstract β-Adrenergic receptor blockers or β-blockers represent one of the oldest classes of
cardiovascular agents and have been considered a cornerstone therapy for hypertension
and heart disease for the past 5 decades. They are advocated as a first-line treatment for
uncomplicated essential hypertension in patients younger than 60 years of age as
recommended by the Canadian Hypertension Education Program. However, despite the
well-established antihypertensive and cardiovascular benefits of β-blockers, a number of …