Novel functions of renin precursors in homeostasis and disease

RA Gomez, MLS Sequeira-Lopez - Physiology, 2016 - journals.physiology.org
RA Gomez, MLS Sequeira-Lopez
Physiology, 2016journals.physiology.org
Renin progenitors appear early and are found in multiple tissues throughout the embryo.
Besides their well known role in blood pressure and fluid homeostasis, renin progenitors
participate in tissue morphogenesis, repair, and regeneration, and may integrate immune
and endocrine responses. In the bone marrow, renin cells offer clues to understand normal
and neoplastic hematopoiesis.
Renin progenitors appear early and are found in multiple tissues throughout the embryo. Besides their well known role in blood pressure and fluid homeostasis, renin progenitors participate in tissue morphogenesis, repair, and regeneration, and may integrate immune and endocrine responses. In the bone marrow, renin cells offer clues to understand normal and neoplastic hematopoiesis.
American Physiological Society