Enhanced production of monocyte chemoattractant protein-1 in the dorsal root ganglia in a rat model of neuropathic pain: possible involvement in the development of …
T Tanaka, M Minami, T Nakagawa, M Satoh - Neuroscience research, 2004 - Elsevier
Chemokines are a family of peptides originally identified as the factors regulating the
migration of leukocytes in inflammatory and immune responses. Recently, they have been
shown to be produced in the central and peripheral nervous systems under various
pathological conditions and act on neuronal and glial cells. In this study, we examined the
production of monocyte chemoattractant protein-1 (MCP-1), a well-characterized chemokine,
in dorsal root ganglia (DRG) in a rat model of neuropathic pain. Partial ligation of the sciatic …
migration of leukocytes in inflammatory and immune responses. Recently, they have been
shown to be produced in the central and peripheral nervous systems under various
pathological conditions and act on neuronal and glial cells. In this study, we examined the
production of monocyte chemoattractant protein-1 (MCP-1), a well-characterized chemokine,
in dorsal root ganglia (DRG) in a rat model of neuropathic pain. Partial ligation of the sciatic …