Morphine stimulates HIV replication in primary cultures of human Kupffer cells
C Schweitzer, F Keller, MP Schmitt, D Jaeck, M Adloff… - Research in …, 1991 - Elsevier
Intravenous drug abusers represent a high risk group for HIV infection in Europe and North
America. Although the use of blood-contaminated needles undoubtedly constitutes the main
factor of transmission of the virus, an effect of the drug itself either on the immune system or
on virus replication, thus favouring the initiation of the infection, may not be excluded. We
have formerly established that primary cultures of human Kupffer cells (KC) are permissive
for HIV1. In this paper, we describe the effect of morphine hydrochloride on the multiplication …
America. Although the use of blood-contaminated needles undoubtedly constitutes the main
factor of transmission of the virus, an effect of the drug itself either on the immune system or
on virus replication, thus favouring the initiation of the infection, may not be excluded. We
have formerly established that primary cultures of human Kupffer cells (KC) are permissive
for HIV1. In this paper, we describe the effect of morphine hydrochloride on the multiplication …