[HTML][HTML] Immunopathogenesis and immunotherapy in AIDS virus infections

NL Letvin, BD Walker - Nature medicine, 2003 - nature.com
NL Letvin, BD Walker
Nature medicine, 2003nature.com
The heterogeneity of HIV and the different human leukocyte antigen (HLA) backgrounds of
infected individuals have posed challenges to understanding the pathogenesis of HIV
infection. But continuing advances in our knowledge of the role of immune responses in
controlling HIV viremia should help to define goals for immune-based therapies and vaccine
strategies against AIDS.
Abstract
The heterogeneity of HIV and the different human leukocyte antigen (HLA) backgrounds of infected individuals have posed challenges to understanding the pathogenesis of HIV infection. But continuing advances in our knowledge of the role of immune responses in controlling HIV viremia should help to define goals for immune-based therapies and vaccine strategies against AIDS.
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