[HTML][HTML] Scavenger receptor, class B, type I-dependent stimulation of cholesterol esterification by high density lipoproteins, low density lipoproteins, and nonlipoprotein …
H Stangl, G Cao, KL Wyne, HH Hobbs - Journal of Biological Chemistry, 1998 - ASBMB
Scavenger receptor, class B, type I (SR-BI) is a cell surface glycoprotein that mediates
selective uptake and efflux of sterols from high density lipoproteins (HDL) to cells. A Chinese
hamster ovary cell line that is deficient in functional LDL receptors, but has high expression
levels of recombinant SR-BI (ldlA7-SR-BI), was used to examine the effect of SR-BI on the
trafficking of sterols between lipoproteins and cells. To monitor the fate of sterols transported
by SR-BI into cells, we measured the incorporation of [14 C] oleate into cholesterol esters by …
selective uptake and efflux of sterols from high density lipoproteins (HDL) to cells. A Chinese
hamster ovary cell line that is deficient in functional LDL receptors, but has high expression
levels of recombinant SR-BI (ldlA7-SR-BI), was used to examine the effect of SR-BI on the
trafficking of sterols between lipoproteins and cells. To monitor the fate of sterols transported
by SR-BI into cells, we measured the incorporation of [14 C] oleate into cholesterol esters by …