In recent years, roles of the immune system in immune surveillance of cancer have been
explored using a variety of approaches. The roles of the adaptive immune system have been
a major emphasis, but increasing evidence supports a role for innate immune effector cells
such as natural killer (NK) cells in tumor surveillance. Here, we discuss some of the
evidence for roles in tumor surveillance of innate immune cells. In particular, we focus on NK
cells and other immune cells that express germline-encoded receptors, often labeled NK …