Towards a standardization of the murine ferric chloride‐induced carotid arterial thrombosis model

AP OWENS III, Y Lu, HC Whinna, C Gachet… - Journal of Thrombosis …, 2011 - jthjournal.org
Mouse models of thrombosis have played a vital role in understanding the pathological
process of thrombus formation in vivo [1–3]. The most commonly used model is ferric
chloride (FeCl3) injury of the carotid artery. The goal of this report from the Animal Models
Subcommittee of the International Society of Thrombosis and Hemostasis is to standardize
this model.