Glucose transporters and insulin action—implications for insulin resistance and diabetes mellitus
PR Shepherd, BB Kahn - New England journal of medicine, 1999 - Mass Medical Soc
PR Shepherd, BB Kahn
New England journal of medicine, 1999•Mass Medical SocInsulin was discovered more than 75 years ago, but only recently have we begun to
understand the mechanisms by which insulin promotes the uptake of glucose into cells. This
review discusses recent advances, their contribution to our understanding of the
pathogenesis of diabetes mellitus, and their implications for the design of new therapies to
prevent and treat diabetes and its complications. Role of Glucose Transporters in
Maintaining Glucose Homeostasis Carbohydrates, and glucose in particular, are an …
understand the mechanisms by which insulin promotes the uptake of glucose into cells. This
review discusses recent advances, their contribution to our understanding of the
pathogenesis of diabetes mellitus, and their implications for the design of new therapies to
prevent and treat diabetes and its complications. Role of Glucose Transporters in
Maintaining Glucose Homeostasis Carbohydrates, and glucose in particular, are an …
Insulin was discovered more than 75 years ago, but only recently have we begun to understand the mechanisms by which insulin promotes the uptake of glucose into cells. This review discusses recent advances, their contribution to our understanding of the pathogenesis of diabetes mellitus, and their implications for the design of new therapies to prevent and treat diabetes and its complications.
Role of Glucose Transporters in Maintaining Glucose Homeostasis
Carbohydrates, and glucose in particular, are an important source of energy for most living organisms. Tissues such as the brain need glucose constantly, and low blood concentrations of glucose can cause . . .
The New England Journal Of Medicine