Autotomy following peripheral nerve lesions: experimental anesthesia dolorosa
PD Wall, M Devor, R Inbal, JW Scadding, D Schonfeld… - Pain, 1979 - Elsevier
(1) When hindlimb peripheral nerves are cut across in rats and mice, there is a tendency for
the animal to attack the anaesthetic limb. We have called this attack “autotomy”. In this paper
we describe the time course and degree of autotomy following various types of nerve injury.
2.(2) Four different types of lesion were applied to the sciatic nerve of rats. The most serious
autotomy was produced by section of the nerve and encapsulation of its cut end in a
polythene tube. Section followed by immediate resuturing also produced serious autotomy …
the animal to attack the anaesthetic limb. We have called this attack “autotomy”. In this paper
we describe the time course and degree of autotomy following various types of nerve injury.
2.(2) Four different types of lesion were applied to the sciatic nerve of rats. The most serious
autotomy was produced by section of the nerve and encapsulation of its cut end in a
polythene tube. Section followed by immediate resuturing also produced serious autotomy …