Chronic granulomatous disease (CGD) is characterized by recurrent infections and
granuloma formation. In addition, we have observed a number of diverse autoimmune
conditions in our CGD population, suggesting that patients with CGD are at an elevated risk
for development of autoimmune disorders. In this report, we describe antiphospholipid
syndrome, recurrent pericardial effusion, juvenile idiopathic arthritis, IgA nephropathy,
cutaneous lupus erythematosus, and autoimmune pulmonary disease in the setting of CGD …