Chronic granulomatous disease (CGD) still causes significant morbidity and mortality. The
difficulty in considering high-risk yet curative treatments, such as allogeneic bone marrow
transplantation, lies in the unpredictable courses of both CGD and bone marrow
transplantation in different patients. Some patients with CGD can have frequent infections,
granulomatous or autoimmune disorders necessitating immunosuppressive therapy, or both
but also experience long periods of relative good health. However, the risk of death is clearly …