[HTML][HTML] Genetic polymorphisms in non-alcoholic fatty liver disease in obese Egyptian children
NM El-Koofy, HM El-Karaksy, IM Mandour… - Saudi Journal of …, 2011 - journals.lww.com
Results: Eight had biopsy-proven simple steatosis and 7 had NASH. NASH patients had a
much higher incidence of the MTP G/G genotype (P= 0.002, CI: 2.9–392) compared with the
controls. NASH patients also had a 100% prevalence of the MnSOD T/T genotype.
Conclusion: Certain genotypes in MTP and MnSOD are significantly more prevalent among
obese children with NASH and may be responsible for such a phenotype.
much higher incidence of the MTP G/G genotype (P= 0.002, CI: 2.9–392) compared with the
controls. NASH patients also had a 100% prevalence of the MnSOD T/T genotype.
Conclusion: Certain genotypes in MTP and MnSOD are significantly more prevalent among
obese children with NASH and may be responsible for such a phenotype.