Non-alcoholic fatty liver disease (NAFLD) is an increasingly reported pathology,
characterized by fat accumulation within the hepatocyte. Growing evidences suggest
specific effects on mitochondrial metabolism, but it is still unclear the relationship between
fatty liver progression and mitochondrial function. In the present work we have investigated
the impact of fatty liver on mitochondrial bioenergetic functions and susceptibility to
mitochondrial permeability transition (MPT) induction in animals fed a choline-deficient diet …