The biological chemistry of hydrogen peroxide
CC Winterbourn - Methods in enzymology, 2013 - Elsevier
Hydrogen peroxide is generated in numerous biological processes and is implicated as the
main transmitter of redox signals. Although a strong oxidant, high activation energy barriers
make it unreactive with most biological molecules. It reacts directly with thiols, but for low-
molecular-weight thiols and cysteine residues in most proteins, the reaction is slow. The
most favored reactions of hydrogen peroxide are with transition metal centers,
selenoproteins, and selected thiol proteins. These include proteins such as catalase …
main transmitter of redox signals. Although a strong oxidant, high activation energy barriers
make it unreactive with most biological molecules. It reacts directly with thiols, but for low-
molecular-weight thiols and cysteine residues in most proteins, the reaction is slow. The
most favored reactions of hydrogen peroxide are with transition metal centers,
selenoproteins, and selected thiol proteins. These include proteins such as catalase …