Neutrophil‐lymphocyte ratio as a prognostic factor in colorectal cancer
SR Walsh, EJ Cook, F Goulder… - Journal of surgical …, 2005 - Wiley Online Library
SR Walsh, EJ Cook, F Goulder, TA Justin, NJ Keeling
Journal of surgical oncology, 2005•Wiley Online LibraryAbstract Background and Objectives Simple methods to identify colorectal cancer patients at
risk of recurrence are needed. This study aimed to determine if neutrophil‐to‐lymphocyte
ratio (NLR) predicts survival in colorectal cancer patients. Methods Two‐hundred thirty
patients diagnosed with colorectal cancer over a two‐year period were identified from a
prospectively maintained colorectal cancer database. NLR was calculated from pre‐
operative full blood counts. In the case of patients who did not undergo surgery, the full …
risk of recurrence are needed. This study aimed to determine if neutrophil‐to‐lymphocyte
ratio (NLR) predicts survival in colorectal cancer patients. Methods Two‐hundred thirty
patients diagnosed with colorectal cancer over a two‐year period were identified from a
prospectively maintained colorectal cancer database. NLR was calculated from pre‐
operative full blood counts. In the case of patients who did not undergo surgery, the full …
Background and Objectives
Simple methods to identify colorectal cancer patients at risk of recurrence are needed. This study aimed to determine if neutrophil‐to‐lymphocyte ratio (NLR) predicts survival in colorectal cancer patients.
Methods
Two‐hundred thirty patients diagnosed with colorectal cancer over a two‐year period were identified from a prospectively maintained colorectal cancer database. NLR was calculated from pre‐operative full blood counts. In the case of patients who did not undergo surgery, the full blood count from their out‐patient visit was used. Known prognostic factors were recorded. Overall and cancer‐specific survival were calculated.
Results
Pre‐operative NLR greater than 5 correlated with overall and cancer‐specific survival in univariate analyses. NLR was not independent of Dukes stage.
Conclusions
Pre‐operative NLR may represent a simple method of identifying colorectal cancer patients with a poor prognosis pre‐operatively. J. Surg. Oncol. 2005;91:181–184. © 2005 Wiley‐Liss, Inc.
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