VEGF receptor signal transduction–A brief update

L Claesson-Welsh - Vascular pharmacology, 2016 - Elsevier
Vascular endothelial growth factor (VEGF) signal transduction through receptor tyrosine
kinases VEGF receptor-1,-2 and-3 is of crucial importance for monocytes/macrophages,
blood vascular endothelial and lymphatic endothelial cells both in physiology and in a
number of pathologies notably cancer. This brief review summarizes the current status of
VEGF receptor signaling with emphasis on in vivo data.