[HTML][HTML] The discovery of cholera-like enterotoxins produced by Escherichia coli causing secretory diarrhoea in humans

RB Sack - Indian Journal of Medical Research, 2011 - journals.lww.com
Non-vibrio cholera has been recognized as a clinical entity for as long as cholera was
known to be caused by Vibrio cholerae. Until 1968, the aetiologic agent of this syndrome
was not known. Following a series of studies in patients with non-vibrio cholera it was found
that these patients had large concentrations of Escherichia coli in the small bowel and stools
which produced cholera toxin-like enterotoxins, and had fluid and electrolyte transport
abnormalities in the small bowel similar to patients with documented cholera. Furthermore …