Tumor endothelial marker 7 (TEM-7): a novel target for antiangiogenic therapy
RG Bagley, C Rouleau, W Weber, K Mehraein… - Microvascular …, 2011 - Elsevier
Antiangiogenesis has been validated as a therapeutic strategy to treat cancer, however, a
need remains to identify new targets and therapies for specific diseases and to improve
clinical benefit from antiangiogenic agents. Tumor endothelial marker 7 (TEM-7) was
investigated as a possible target for therapeutic antiangiogenic intervention in cancer. TEM-
7 expression was assessed by in situ hybridization or by immunohistochemistry (IHC) in 130
formalin-fixed paraffin-embedded (FFPE) and 410 frozen human clinical specimens of …
need remains to identify new targets and therapies for specific diseases and to improve
clinical benefit from antiangiogenic agents. Tumor endothelial marker 7 (TEM-7) was
investigated as a possible target for therapeutic antiangiogenic intervention in cancer. TEM-
7 expression was assessed by in situ hybridization or by immunohistochemistry (IHC) in 130
formalin-fixed paraffin-embedded (FFPE) and 410 frozen human clinical specimens of …