[HTML][HTML] Bioactive products formed in humans from fish oils1 [S]

C Skarke, N Alamuddin, JA Lawson, X Li… - Journal of lipid …, 2015 - ASBMB
Resolvins, maresins, and protectins can be formed from fish oils. These specialized pro-
resolving mediators (SPMs) have been implicated in the resolution of inflammation.
Synthetic versions of such SPMs exert anti-inflammatory effects in vitro and when
administered to animal models. However, their importance as endogenous products formed
in sufficient amounts to exert anti-inflammatory actions in vivo remains speculative. We
biased our ability to detect SPMs formed in healthy volunteers by supplementing fish oil in …