Hypersensitivity reactions during therapy with the nucleoside reverse transcriptase inhibitor abacavir
S Hetherington, S McGuirk, G Powell, A Cutrell… - Clinical …, 2001 - Elsevier
Background: Hypersensitivity reactions consist of a variable group of clinical findings and
have been described for a wide variety of chemical compounds. Objective: This review
characterizes the clinical profile of hypersensitivity to the nucleoside reverse transcriptase
inhibitor abacavir sulfate. Methods: We performed a retrospective medical review of pooled
adverse events data from∼ 200,000 patients who received abacavir in clinical trials, through
expanded-access programs, or by prescription from 1996 through 2000. Screened cases of …
have been described for a wide variety of chemical compounds. Objective: This review
characterizes the clinical profile of hypersensitivity to the nucleoside reverse transcriptase
inhibitor abacavir sulfate. Methods: We performed a retrospective medical review of pooled
adverse events data from∼ 200,000 patients who received abacavir in clinical trials, through
expanded-access programs, or by prescription from 1996 through 2000. Screened cases of …