Response to live attenuated measles vaccine in children with severe kwashiorkor
GM Powell - Annals of tropical paediatrics, 1982 - Taylor & Francis
GM Powell
Annals of tropical paediatrics, 1982•Taylor & FrancisAn impaired response to vaccination with live attenuated measles vaccine was found in
severely malnourished children, when compared with well nourished controls. It is
suggested that humoral immune response may fail in children with severe protein energy
malnutrition due to diversion of available amino acids to other uses. The possibility of a
delayed antibody response to measles vaccine in malnourished children was not excluded.
severely malnourished children, when compared with well nourished controls. It is
suggested that humoral immune response may fail in children with severe protein energy
malnutrition due to diversion of available amino acids to other uses. The possibility of a
delayed antibody response to measles vaccine in malnourished children was not excluded.
Summary
An impaired response to vaccination with live attenuated measles vaccine was found in severely malnourished children, when compared with well nourished controls. It is suggested that humoral immune response may fail in children with severe protein energy malnutrition due to diversion of available amino acids to other uses. The possibility of a delayed antibody response to measles vaccine in malnourished children was not excluded.
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