Lupus erythematosus (LE) is a disease with a wide spectrum of cutaneous and systemic
manifestations. Clinical features of patients with LE show a great variation, and for this
reason it is difficult to develop a unifying concept of this disease. Our objective is to present a
case of hypertrophic LE with atypical morphology and extensive involvement, who
responded favorably to isotretinoin. Diagnosis of hypertrophic lupus erythematosus (HLE)
was confirmed by characteristic histopathological findings. Combination therapy with …