Perivascular carotid collar placement induces neointima formation and outward arterial remodeling in mice independent of apolipoprotein E deficiency or Western …
R Baetta, F Silva, C Comparato, M Uzzo, I Eberini… - Atherosclerosis, 2007 - Elsevier
We investigated the influence of apolipoprotein E deficiency and Western-type diet feeding
on the development and composition of neointimal lesions induced by periadventitial carotid
placement of a non-occlusive collar in mice. ApoE−/− and wild-type mice were fed a Western-
type diet or chow diet for 4 weeks before collar surgery. Diets were continued after collar
placement for 6 or 12 weeks. Compared to sham-operated arteries, collared carotids
showed significant neointima formation, lumen loss, and outward remodeling in both …
on the development and composition of neointimal lesions induced by periadventitial carotid
placement of a non-occlusive collar in mice. ApoE−/− and wild-type mice were fed a Western-
type diet or chow diet for 4 weeks before collar surgery. Diets were continued after collar
placement for 6 or 12 weeks. Compared to sham-operated arteries, collared carotids
showed significant neointima formation, lumen loss, and outward remodeling in both …