Intratumoral neutrophils: a poor prognostic factor for hepatocellular carcinoma following resection
YW Li, SJ Qiu, J Fan, J Zhou, Q Gao, YS Xiao… - Journal of hepatology, 2011 - Elsevier
BACKGROUND & AIMS: Neutrophil infiltration has been linked to clinical outcome of various
cancer types. However, its role in hepatocellular carcinoma (HCC) is unclear. In this study,
we investigated prognostic values for intratumoral and peritumoral neutrophils in HCC
patients undergoing curative resection. METHODS: The expression of CD66b, CD8, TGF-
beta, and CD34 was assessed by immunohistochemistry in tissue microarrays containing
paired intratumoral and peritumoral tissues from 197 patients receiving curative resection for …
cancer types. However, its role in hepatocellular carcinoma (HCC) is unclear. In this study,
we investigated prognostic values for intratumoral and peritumoral neutrophils in HCC
patients undergoing curative resection. METHODS: The expression of CD66b, CD8, TGF-
beta, and CD34 was assessed by immunohistochemistry in tissue microarrays containing
paired intratumoral and peritumoral tissues from 197 patients receiving curative resection for …