Prevalence of pulmonary embolism in acute exacerbations of COPD: a systematic review and metaanalysis

J Rizkallah, SFP Man, DD Sin - Chest, 2009 - Elsevier
Background Nearly 30% of all exacerbations of COPD do not have a clear etiology.
Although pulmonary embolism (PE) can exacerbate respiratory symptoms such as dyspnea
and chest pain, and COPD patients are at a high risk for PE due to a variety of factors
including limited mobility, inflammation, and comorbidities, the prevalence of PE during
exacerbations is uncertain. Methods A systematic review of the literature was performed to
determine the reported prevalence of PE in acute exacerbations of COPD in patients who …