Neutrophil gelatinase-associated lipocalin: a biomarker in COPD

TM Eagan, JK Damås, T Ueland, M Voll-Aanerud… - Chest, 2010 - Elsevier
Background Neutrophil gelatinase-associated lipocalin (NGAL) is an antimicrobial peptide
that could be involved in the pathogenesis of COPD. This study aimed to measure the
plasma levels of NGAL in a large cohort of patients with COPD and control subjects and
examine the levels of NGAL by COPD characteristics. Methods The study included 402
patients with COPD and 229 control subjects aged 40 to 76 years from the Bergen COPD
Cohort Study. All patients with COPD had an FEV 1/FVC ratio of< 0.7, an FEV 1< 80 …