Structural and functional recovery following limited iatrogenic macular detachment for retinal gene therapy

MP Simunovic, K Xue, JK Jolly… - JAMA …, 2017 - jamanetwork.com
Importance The early decline and recovery of retinal structure and function following
iatrogenic macular detachment for retinal gene therapy is not well characterized in those
with relatively preserved central visual function. Here, the recovery of retinal structure and
function over the first month following iatrogenic retinal detachment for the delivery of adeno-
associated viral vector encoding Rab Escort Protein 1 is described as a part of gene therapy
for choroideremia. Objective To study changes in both retinal structure and function during …