Analgesic effects of intravenous lidocaine and morphine on postamputation pain: a randomized double-blind, active placebo-controlled, crossover trial
CL Wu, P Tella, PS Staats, R Vaslav… - The Journal of the …, 2002 - pubs.asahq.org
Background Phantom and stump pains, common sequelae of limb amputations, are
significant impediments to rehabilitation of amputees. The pathophysiology and optimal
treatment of postamputation pain states are unclear. While stump pain may result from
neuromas in the stump, phantom pain is thought to be related to cortical reorganization. The
authors hypothesized that morphine and lidocaine may have differential effectiveness on
stump and phantom pains. Methods The authors conducted a randomized double-blind …
significant impediments to rehabilitation of amputees. The pathophysiology and optimal
treatment of postamputation pain states are unclear. While stump pain may result from
neuromas in the stump, phantom pain is thought to be related to cortical reorganization. The
authors hypothesized that morphine and lidocaine may have differential effectiveness on
stump and phantom pains. Methods The authors conducted a randomized double-blind …