Angiogenesis and endothelial cell repair in renal disease and allograft rejection
MEJ Reinders, TJ Rabelink… - Journal of the American …, 2006 - journals.lww.com
This review discusses the concept that the turnover and replacement of endothelial cells is a
major mechanism in the maintenance of vascular integrity within the kidney. CD133+ CD34+
KDR+ endothelial cell progenitor cells emigrate from the bone marrow and differentiate into
CD34+ KDR+ expressing cells, which are present in high numbers within the circulation.
These progenitor cells are available for recruitment into normal or inflamed tissues to
facilitate endothelial cell repair. In several forms of renal disease, proinflammatory insults …
major mechanism in the maintenance of vascular integrity within the kidney. CD133+ CD34+
KDR+ endothelial cell progenitor cells emigrate from the bone marrow and differentiate into
CD34+ KDR+ expressing cells, which are present in high numbers within the circulation.
These progenitor cells are available for recruitment into normal or inflamed tissues to
facilitate endothelial cell repair. In several forms of renal disease, proinflammatory insults …