[HTML][HTML] Analysis of the MRP8-MRP14 protein-protein interaction by the two-hybrid system suggests a prominent role of the C-terminal domain of S100 proteins in …
C Pröpper, X Huang, J Roth, C Sorg… - Journal of Biological …, 1999 - ASBMB
Calcium-binding S100 proteins are thought to play a central role in calcium-mediated signal
transduction pathways. They consist of two helix-loop-helix, calcium-binding EF-hand
domains. A characteristic feature is their tendency to form homo-and/or heterodimeric
complexes. This report presents for the first time a functional" in vivo" approach to the
analysis of S100 protein dimerization. Using the two-hybrid system we analyzed the
dimerization of MRP8 (S100A8) and MRP14 (S100A9), two S100 proteins expressed in …
transduction pathways. They consist of two helix-loop-helix, calcium-binding EF-hand
domains. A characteristic feature is their tendency to form homo-and/or heterodimeric
complexes. This report presents for the first time a functional" in vivo" approach to the
analysis of S100 protein dimerization. Using the two-hybrid system we analyzed the
dimerization of MRP8 (S100A8) and MRP14 (S100A9), two S100 proteins expressed in …