Murine echocardiography and ultrasound imaging

A Pistner, S Belmonte, T Coulthard… - JoVE (Journal of Visualized …, 2010 - jove.com
Rodent models of cardiac pathophysiology represent a valuable research tool to investigate
mechanism of disease as well as test new therapeutics. 1 Echocardiography provides a
powerful, non-invasive tool to serially assess cardiac morphometry and function in a living
animal. 2 However, using this technique on mice poses unique challenges owing to the
small size and rapid heart rate of these animals. 3 Until recently, few ultrasound systems
were capable of performing quality echocardiography on mice, and those generally lacked …