SOX genes encode a family of high-mobility group transcription factors that play critical roles
in organogenesis. The functional specificity of different SOX proteins and the tissue
specificity of a particular SOX factor are largely determined by the differential partnership of
SOX transcription factors with other transcription regulators, many of which have not yet
been discovered. Virtually all members of the SOX family have been found to be
deregulated in a wide variety of tumors. However, little is known about the cellular and …