[HTML][HTML] Stearoyl CoA desaturase 1: role in cellular inflammation and stress
X Liu, MS Strable, JM Ntambi - Advances in nutrition, 2011 - Elsevier
ABSTRACT Stearoyl CoA desaturase 1 (SCD1) catalyzes the rate-limiting step in the
production of MUFA that are major components of tissue lipids. Alteration in SCD1
expression changes the fatty acid profile of these lipids and produces diverse effects on
cellular function. High SCD1 expression is correlated with metabolic diseases such as
obesity and insulin resistance, whereas low levels are protective against these metabolic
disturbances. However, SCD1 is also involved in the regulation of inflammation and stress in …
production of MUFA that are major components of tissue lipids. Alteration in SCD1
expression changes the fatty acid profile of these lipids and produces diverse effects on
cellular function. High SCD1 expression is correlated with metabolic diseases such as
obesity and insulin resistance, whereas low levels are protective against these metabolic
disturbances. However, SCD1 is also involved in the regulation of inflammation and stress in …