Axillary dissection vs no axillary dissection in women with invasive breast cancer and sentinel node metastasis: a randomized clinical trial
AE Giuliano, KK Hunt, KV Ballman, PD Beitsch… - Jama, 2011 - jamanetwork.com
Context Sentinel lymph node dissection (SLND) accurately identifies nodal metastasis of
early breast cancer, but it is not clear whether further nodal dissection affects survival.
Objective To determine the effects of complete axillary lymph node dissection (ALND) on
survival of patients with sentinel lymph node (SLN) metastasis of breast cancer. Design,
Setting, and Patients The American College of Surgeons Oncology Group Z0011 trial, a
phase 3 noninferiority trial conducted at 115 sites and enrolling patients from May 1999 to …
early breast cancer, but it is not clear whether further nodal dissection affects survival.
Objective To determine the effects of complete axillary lymph node dissection (ALND) on
survival of patients with sentinel lymph node (SLN) metastasis of breast cancer. Design,
Setting, and Patients The American College of Surgeons Oncology Group Z0011 trial, a
phase 3 noninferiority trial conducted at 115 sites and enrolling patients from May 1999 to …