[CITATION][C] Karnofsky Memorial Lecture. Natural history of small breast cancers
S Hellman - Journal of clinical oncology: official journal of …, 1994 - pubmed.ncbi.nlm.nih.gov
[PDF][PDF] Natural history of small breast cancers
S Hellman, KM Lecture - Journal of clinical oncology, 1994 - Citeseer
PROGRESS IN MEDICINE, like evolution, appears to occur in fits and starts, that is, there
appear to be long periods of quiescence and then great bursts of insight into the etiology,
natural history, and therapy of particular diseases. With breast cancer, the notion of the
disease, its pathogenesis, and its treatment remained relatively static following the
formulation of the Halsted paradigm for the disease and the acceptance of radical
mastectomy as the logical therapeutic embodiment of this notion of disease spread. 1, 2 Fin …
appear to be long periods of quiescence and then great bursts of insight into the etiology,
natural history, and therapy of particular diseases. With breast cancer, the notion of the
disease, its pathogenesis, and its treatment remained relatively static following the
formulation of the Halsted paradigm for the disease and the acceptance of radical
mastectomy as the logical therapeutic embodiment of this notion of disease spread. 1, 2 Fin …