To the Editor: We report a case of fatal melanoma that had been transferred in a donated kidney and that occurred 16 years after surgery for primary melanoma in the donor. A woman with polycystic disease received a renal transplant in May 1998. The graft functioned well. In November 1999, routine mammography showed a nodule in the left breast, and a biopsy specimen was obtained. Primary breast cancer was diagnosed. Pain and swelling then developed over the renal transplant, and two subcutaneous nodules were found. Biopsy confirmed the presence of secondary melanoma. No primary melanoma was identified. The pathological features . . .