Expression of gamma/delta T cell receptors on lymphocytes from the lactating mammary gland.

C Reardon, L Lefrancois, A Farr, R Kubo… - The Journal of …, 1990 - rupress.org
C Reardon, L Lefrancois, A Farr, R Kubo, R O'Brien, W Born
The Journal of experimental medicine, 1990rupress.org
gamma/delta cells were at least four times more frequent in lactating mouse mammary
glands than among T cells of the most proximal lymph nodes. Two-color staining of freshly
isolated T cells and a study of clonally expressed gamma/delta receptors on hybridomas
further revealed that the mammary gamma/delta population is heterogeneous, including at
least three different subsets, among them cells expressing V gamma 5, V gamma 4 together
with V delta 4, or none of these V regions.
gamma/delta cells were at least four times more frequent in lactating mouse mammary glands than among T cells of the most proximal lymph nodes. Two-color staining of freshly isolated T cells and a study of clonally expressed gamma/delta receptors on hybridomas further revealed that the mammary gamma/delta population is heterogeneous, including at least three different subsets, among them cells expressing V gamma 5, V gamma 4 together with V delta 4, or none of these V regions.
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