Toxic epidermal necrolysis: clinical findings and prognosis factors in 87 patients

J Revuz, D Penso, JC Roujeau… - Archives of …, 1987 - jamanetwork.com
• Eighty-seven patients with toxic epidermal necrolysis were observed at Hôpital Henri
Mondor in Créteil, France, over the last 12 years. The mean percentage of body surface area
involved was 39%. Erosive mucous membrane lesions, identical to those of Stevens-
Johnson syndrome, were present in all but three cases. Necrolysis was sometimes
generalized within 24 hours but usually spread progressively after a Stevens-Johnson
syndrome—like aspect at the onset. Mortality was 25%. Infection, mainly withStaphylococus …