Effect of physical activity on cognitive function in older adults at risk for Alzheimer disease: a randomized trial

NT Lautenschlager, KL Cox, L Flicker, JK Foster… - Jama, 2008 - jamanetwork.com
Context Many observational studies have shown that physical activity reduces the risk of
cognitive decline; however, evidence from randomized trials is lacking. Objective To
determine whether physical activity reduces the rate of cognitive decline among older adults
at risk. Design and Setting Randomized controlled trial of a 24-week physical activity
intervention conducted between 2004 and 2007 in metropolitan Perth, Western Australia.
Assessors of cognitive function were blinded to group membership. Participants We …