Bone marrow-derived progenitor cells have recently been shown to be involved in the
development of intimal hyperplasia after vascular injury. Transforming growth factor-β (TGF-
β) has profound stimulatory effects on intimal hyperplasia, but it is unknown whether these
effects involve progenitor cell recruitment. In this study we found that although TGF-β had no
direct effect on progenitor cell recruitment, conditioned media derived from vascular smooth
muscle cells (VSMC) stimulated with TGF-β induced migration of both total bone marrow …