[HTML][HTML] Characterization of a subset of the basic-helix-loop-helix-PAS superfamily that interacts with components of the dioxin signaling pathway
JB Hogenesch, WK Chan, VH Jackiw, RC Brown… - Journal of Biological …, 1997 - ASBMB
In an effort to better understand the mechanism of toxicity of 2, 3, 7, 8-tetrachlorodibenzo-p-
dioxin, we employed an iterative search of human expressed sequence tags to identify novel
basic-helix-loop-helix-PAS (bHLH-PAS) proteins that interact with either the Ah receptor
(AHR) or the Ah receptor nuclear translocator (ARNT). We characterized five new" embers f
the AS superfamily," or MOPs 1-5, that are similar in size and structural organization to the
AHR and ARNT. MOPs 1-4 have N-terminal bHLH and PAS domains and C-terminal …
dioxin, we employed an iterative search of human expressed sequence tags to identify novel
basic-helix-loop-helix-PAS (bHLH-PAS) proteins that interact with either the Ah receptor
(AHR) or the Ah receptor nuclear translocator (ARNT). We characterized five new" embers f
the AS superfamily," or MOPs 1-5, that are similar in size and structural organization to the
AHR and ARNT. MOPs 1-4 have N-terminal bHLH and PAS domains and C-terminal …