Insulin resistance and compensatory hyperinsulinemia: role in hypertension, dyslipidemia, and coronary heart disease
GM Reaven - American heart journal, 1991 - Elsevier
GM Reaven
American heart journal, 1991•ElsevierResistance to insulin-stimulated glucose uptake and hyperinsulinemia may play a central
role in the cause and clinical course of patients with non-insulin-dependent diabetes
mellitus, high blood pressure, abnormalities of lipoprotein metabolism, and coronary heart
disease. This article summarizes the evidence in support of this general hypothesis.
role in the cause and clinical course of patients with non-insulin-dependent diabetes
mellitus, high blood pressure, abnormalities of lipoprotein metabolism, and coronary heart
disease. This article summarizes the evidence in support of this general hypothesis.
Abstract
Resistance to insulin-stimulated glucose uptake and hyperinsulinemia may play a central role in the cause and clinical course of patients with non-insulin-dependent diabetes mellitus, high blood pressure, abnormalities of lipoprotein metabolism, and coronary heart disease. This article summarizes the evidence in support of this general hypothesis.
Elsevier