Fructose consumption as a risk factor for non-alcoholic fatty liver disease
BACKGROUND/AIMS: While the rise in non-alcoholic fatty liver disease (NAFLD) parallels
the increase in obesity and diabetes, a significant increase in dietary fructose consumption
in industrialized countries has also occurred. The increased consumption of high fructose
corn syrup, primarily in the form of soft drinks, is linked with complications of the insulin
resistance syndrome. Furthermore, the hepatic metabolism of fructose favors de novo
lipogenesis and ATP depletion. We hypothesize that increased fructose consumption …
the increase in obesity and diabetes, a significant increase in dietary fructose consumption
in industrialized countries has also occurred. The increased consumption of high fructose
corn syrup, primarily in the form of soft drinks, is linked with complications of the insulin
resistance syndrome. Furthermore, the hepatic metabolism of fructose favors de novo
lipogenesis and ATP depletion. We hypothesize that increased fructose consumption …