Ultrasound imaging of breast tumor perfusion and neovascular morphology
K Hoyt, H Umphrey, M Lockhart, M Robbin… - Ultrasound in medicine …, 2015 - Elsevier
A novel image processing strategy is detailed for simultaneous measurement of tumor
perfusion and neovascular morphology parameters from a sequence of dynamic contrast-
enhanced ultrasound (DCE-US) images. After normalization and tumor segmentation, a
global time–intensity curve describing contrast agent flow was analyzed to derive surrogate
measures of tumor perfusion (ie, peak intensity, time-to-peak intensity, area under the curve,
wash-in rate, wash-out rate). A maximum intensity image was generated from these same …
perfusion and neovascular morphology parameters from a sequence of dynamic contrast-
enhanced ultrasound (DCE-US) images. After normalization and tumor segmentation, a
global time–intensity curve describing contrast agent flow was analyzed to derive surrogate
measures of tumor perfusion (ie, peak intensity, time-to-peak intensity, area under the curve,
wash-in rate, wash-out rate). A maximum intensity image was generated from these same …