[HTML][HTML] No reduction of atherosclerosis in C-reactive protein (CRP)-deficient mice

D Teupser, O Weber, TN Rao, K Sass, J Thiery… - Journal of Biological …, 2011 - ASBMB
C-reactive protein (CRP), a phylogenetically highly conserved plasma protein, is the
classical acute phase reactant in humans. Upon infection, inflammation, or tissue damage,
its plasma level can rise within hours> 1000-fold, providing an early, nonspecific disease
indicator of prime clinical importance. In recent years, another aspect of CRP expression has
attracted much scientific and public attention. Apart from transient, acute phase-associated
spikes in plasma concentration, highly sensitive measurements have revealed stable …