C-reactive protein, interleukin 6, and risk of developing type 2 diabetes mellitus
AD Pradhan, JAE Manson, N Rifai, JE Buring… - Jama, 2001 - jamanetwork.com
ContextInflammation is hypothesized to play a role in development of type 2 diabetes
mellitus (DM); however, clinical data addressing this issue are limited. ObjectiveTo
determine whether elevated levels of the inflammatory markers interleukin 6 (IL-6) and C-
reactive protein (CRP) are associated with development of type 2 DM in healthy middle-
aged women. DesignProspective, nested case-control study. SettingThe Women's Health
Study, an ongoing US primary prevention, randomized clinical trial initiated in 1992 …
mellitus (DM); however, clinical data addressing this issue are limited. ObjectiveTo
determine whether elevated levels of the inflammatory markers interleukin 6 (IL-6) and C-
reactive protein (CRP) are associated with development of type 2 DM in healthy middle-
aged women. DesignProspective, nested case-control study. SettingThe Women's Health
Study, an ongoing US primary prevention, randomized clinical trial initiated in 1992 …